Nadav Schechter

A student's first attempts at a scruff, a gavage or a tail vein are the worst ones. Where the Humaneway simulators from Hundred Medical move those attempts off live animals in Israeli handling courses and lab onboarding, and where they do not.

Five papers, five Alzheimer's-related mechanisms, and the behavioral test each group used to check for a functional effect: fear conditioning, water maze, RotaRod, passive avoidance and grip strength. Ugo Basile's round-up, with the full references.

WPI application note: EVOM Chip measured TEER on-chip in HUVEC monolayers and a primary BBB tri-culture, tracking barrier maturation and the drop after TNF-α. Numbers, methods and the n for each model are all in the post.

Instech walks through rodent IV dosing from a single tail vein bolus to weeks of tethered infusion, and the catheter, button, tether, swivel and pump each approach needs. The catheter section, with patency data for round and blunt tips, is the part most labs should read first.

ibidi's third Flow Meeting runs February 24 to 25, 2027 at the Biomedical Center Munich. Two days on vascular biology, barrier models and cell culture under flow, plus a hands-on Pump System workshop.

Conventional culture leaves out the flow, gradients and tissue contact cells get inside the body. ibidi walks through how organ-on-chip models add that context back, from a single vessel model to a cardiac-kidney system sharing one circulating environment.

Artinis explains why HD-EMG and muscle NIRS work better together. Here is what that means for the SPIRE and PortaMon pairing NBT now carries, and when you do not need both.

For gene modification and transfection work, pipette tip geometry drives delivery efficiency, targeting accuracy, cell viability, and repeatability. Here is why long-taper glass tips are the right default for microinjection-based techniques.

Multi-syringe pumps look economical, but for live-animal infusion in rodents the tradeoffs - no occlusion alarm, awkward dead volumes, forced synchronization, and a single point of failure - usually make one small pump per animal the safer and cleaner choice.

Rodent hemoglobin behaves differently than human hemoglobin, with a higher P50 that means oxygen saturation shifts faster when ventilation, CO₂/pH, and temperature drift. Practical mental model for safer, more repeatable mouse and rat anesthesia workflows.

Precisionary rebuilt the Compresstome bibliography. 315 pages, 22 full protocols, 30 countries. Which part to search, what the ten Israeli entries show, and what the file does not answer.

One vaporizer, three builds. How we scope a SomnoFlo anesthesia setup before it goes to quote: the gas path that writes the parts list, chamber and mask sizes by species, the MRI rule that keeps the vaporizer in the control room, and where not to spend the money.

The SomnoFlo, the endotracheal intubation kit and the RoVent Jr. are bought separately and used as one line. The gas path, the two charcoal canisters this setup needs, the calibration step that decides whether your tidal volumes mean anything, and the settings the ventilator does not calculate for you.

The chip is the cheap part of a lab-on-a-chip, so the money goes on the system around it. This guide walks the fluid path first, run-to-waste or recirculation, and points each to the pump that fits.

Organoids that survive multi-day shipping, retinal organoids with real light responses, APOE4 reshaping development decades before Alzheimer's, and cerebral tissue turned into a live musical composition. Four MEA studies from the past year.

Organoids self-organise but lack vasculature and drift over time. Chips give you perfusion and mechanical control but are laborious to fabricate. Elveflow compares the two model classes honestly, and makes the case for combining them.

Mice cool quickly under anaesthesia, and heat loss often starts during prep rather than during the procedure. Kent Scientific sets out what drives the drop, what it costs in recovery and data variance, and the three-window warming workflow that prevents it.

NBT distributes both NIRx and Artinis in Israel, so this comparison carries no commercial preference in either direction. Modality choice, vendor comparison, channel count and montage, short separation channels, regulatory status, analysis pipeline and synchronisation.

Channel count, dry or wet electrodes, triggers and synchronisation, and who runs the RMA when the amplifier fails. The four questions we work through on the phone before anyone signs a purchase order for research EEG.

Three identical arms and an animal free to choose. Noldus walks through what that single decision reveals about spatial and working memory, and how automated tracking turns arm entries into clean, objective data.

Cells cultured under identical conditions still behave differently, and part of that variability is simply spatial randomness. This ibidi primer explains how micropatterning turns geometry into a controlled experimental parameter.

ibidi's Dr. Abhishek Derle argues that variability, pipetting quirks, moody reagents and human error are features of biology experiments rather than flaws in them, and that messy data is usually where the insight sits.

Noldus' senior trainers answer the most common CatWalk XT questions: which gait parameters to select, how to configure detection settings, how to motivate animals across the walkway, and how to clean the system so the data holds up for publication.

Continuous telemetry produces vast physiological datasets. Advanced analytics tools like Data Insights for Ponemah help researchers move from manual ECG review to targeted, automated, reproducible data validation.

Microbiome research is moving from species-level surveys to strain-level function, and Molecular Devices argues that automation such as the QPix FLEX colony picker is now central to culture-based validation.

A new TSC mouse model shows that deleting Tsc2 in a small area of the frontal cortex is enough to trigger spontaneous seizures and anxiety-like behavior, quantified with automated EthoVision tracking.

Microfluidics is revolutionizing cosmetic research by enabling precise emulsion formulation, high-throughput testing, and ethical skin-on-a-chip models as alternatives to animal testing.

From 2D neuronal cultures to 3D organoids and microfluidic systems, in vitro models of the nervous system offer researchers increasingly sophisticated tools for studying brain development, function, and disease.

Dr. Monica Torres-Ruiz built DanioFlow, a free open-source tool that automates EthoVision data analysis for zebrafish thigmotaxis studies. It came out of her own experimental problems on a neurotoxicity project.

Dolomite Microfluidics was discontinued in 2026. A look at the pressure-based flow controllers still on the market and how to choose between them.

A methodology workshop at Tel Aviv University on preclinical psilocybin research, covering behavioral approaches for measuring drug effects and using EthoVision as the analysis tool. Hosted by the Myers Neuro-Behavioral Core Facility on June 21.

NBT is exhibiting at ILAF 2026, the Israeli Laboratory Animal Forum's annual meeting. On the stand: the new Instech Syringe Pump, iPRECIO micro-infusion pumps, Kent Scientific's SomnoSuite anesthesia system, FST's 2026 catalog and Hundred's surgical components. Come visit our booth.

NBT exhibited at ISM 2026 at Expo Tel Aviv with ibidi chambers and slides for cell culture and microscopy, and the RWD RFLSI-ZW Laser Speckle Imaging System for real-time microcirculation research.

A look at how Dr. Tamar Ben Shaanan's lab at the Weizmann Institute of Science is using the Kent Scientific SomnoFlo® Electronic Vaporizer to deliver precisely controlled isoflurane anesthesia in their work on pain, nociceptors, and tissue regeneration.

Automation and AI are changing cell microscopy, from robotic stages and standardised acquisition to deep learning analysis of 3D organoids. ibidi walks through where each piece fits.

EthoVision's deep learning social tracker measures rodent social interactions with the animals housed together and barely marked, so the data stays clean without adding handling stress.

NBT recently installed a state-of-the-art Smart Ussing chamber system at Prof. Eran Elinav's laboratory at the Weizmann Institute of Science, enabling cutting-edge research into gut epithelial barrier function and microbiome interactions.

A closer look at how Dr. Silvi Frenkel-Toledo's lab at Ariel University's Department of Physiotherapy is using the Mag&More PowerMAG TMS system for advanced brain stimulation research in motor rehabilitation and stroke recovery.

A closer look at how Dr. Tal Iram's lab at the Weizmann Institute of Science is using two RWD Stereotaxic Stations to perform high-precision in vivo surgeries in their research on oligodendrocyte aging, CSF dynamics, and cognitive rejuvenation.

At sub-microliter volumes, four mechanical factors drive inconsistent microinjection: dead volume, air bubbles, plunger stick-slip and manual rate variation. How to eliminate each one.

A 70-cm bronze mouse knitting a DNA double helix sits outside a Siberian research institute. Kent Scientific uses it to talk about what good animal science requires: respect, restraint, rigor and the 3Rs.

A closer look at how Dr. Arseny Finkelstein's neuroscience lab at Tel Aviv University is using the Sensapex Multiprobe Rig for high-precision, multi-site in vivo electrophysiology in mice.

There are a lot of syringe pumps and a lot of specs. These are the factors that decide precision, flow stability and how long the pump lasts.

MindWare Technologies turns 25. CEO Eric Morgan writes about 25 years of work with researchers and what the company is releasing next.

Brain organoids need months of continuous culture. Automation keeps those cultures consistent and reproducible at scale, which is what long-term Alzheimer's and Parkinson's work depends on.

Tail-cuff blood pressure in mice and rats can be fast, scalable and reliable, provided stress, tail perfusion, movement and session design are handled. What the method measures, and the failure modes that catch people out.

As organoid research grows, traditional 2D planar MEAs show clear limitations. Mesh MEA from Multi Channel Systems maintains structural integrity, enables long-term recordings from inside intact 3D organoids, and reduces experimental risk.

Researcher interview: Dr. Gabriel David, head of Biolabs at Synchrotron Soleil, explains how pressure-based microfluidic flow control with Elveflow's OB1 system keeps fragile biological samples intact during synchrotron X-ray experiments.

How to convert a standard Tecniplast rat cage into a tethered infusion cage: slotting the lid, fitting a counter-balanced swivel mount, and picking a tether length that lets the animal move.

A year-end look back at the concepts that ran through human behavior research in 2025: stimulus design, emotional measurement, social interaction coding and observational method.

Dr. Monica Torres-Ruiz explains how a problem on a large neurotoxicity project led her to build DanioFlow, a free open-source tool that simplifies and harmonises EthoVision data analysis for zebrafish thigmotaxis studies.

Material choice decides reliability, precision and compatibility in microfluidics, and it decides them hardest when biological samples are involved. PDMS is still the staple, but PMMA, alginate-based hydrogels and Flexdym are taking work off it. Elveflow goes through where each one fits.

Microfluidics gives precise control over small fluid volumes, but measuring that volume accurately is still hard. Small variations in liquid handling show up in reaction efficiency, reproducibility and data integrity.

Organoid research has evolved rapidly, and offers unprecedented insights into cellular development, disease modeling, and regenerative medicine. A number of notable publications in organoid research have been released this year that provide insight into various biological and medical advancements.

Founded nearly 30 years ago, Multi Channel Systems (MCS) is a pioneer in the development of commercially available microelectrode arrays (MEA) and their recording systems. MEAs have proven valuable for our understanding of how genetic background, disease pathology, and drugs alter neuronal network activity.

Mouse temperature is one of the easiest things to lose control of while believing you are handling it. Core temperature and surface temperature answer different questions, and relying on one leaves a blind spot. Kent Scientific covers continuous versus spot-check, core versus surface, where each fits in anesthesia, recovery and free-moving studies, and a few workflow recipes that improve stability without wrecking throughput.

Everything you need to know about using flexible feeding tubes for rodents

Rodent catheterization raises many questions to mind, particularly regarding surgical equipment and instruments, animal recovery and catheter patency. What surgical equipment should I use? Which tools influence surgical outcomes and animal recovery? What surgical instruments are recommended? How can I minimize trauma during surgery? And what strategies can help extend catheter patency duration?

Some laboratory syringe pumps have a built-in two-syringe rack; others take racks so one pump can push four, six or even 10 syringes at once. Syringe pumps are expensive, so it is tempting to have one pump multi-task. What are the downsides?

Learn about the key scientific methods used in human behavior research. We explain quantitative and qualitative approaches, experimental design, and how researchers collect and analyze behavioral data.