Research Spotlight: Mag&More PowerMAG TMS System at the Frenkel-Toledo Lab, Ariel University

Where Brain Stimulation Science Meets Motor Rehabilitation

At the Frenkel-Toledo Lab in the Department of Physiotherapy at Ariel University, understanding how brain stimulation can restore motor function after stroke and injury demands tools that are both scientifically precise and clinically versatile. That's why the lab has equipped its research suite with the Mag&More PowerMAG TMS System — a state-of-the-art transcranial magnetic stimulation platform engineered for both cutting-edge research and therapeutic applications in neurorehabilitation.

The Mag&More PowerMAG TMS System

The PowerMAG is Mag&More's flagship TMS platform, designed for the full spectrum of transcranial magnetic stimulation applications — from single-pulse motor mapping and cortical excitability assessment to repetitive TMS (rTMS) protocols for research and rehabilitation. The system delivers precise, reproducible magnetic pulses to targeted cortical areas, enabling researchers to non-invasively modulate neural activity and measure its downstream effects on motor performance and recovery.

A key feature of the PowerMAG setup is its dedicated PowerMAG View! software, which provides real-time visualization of stimulation parameters, motor evoked potential (MEP) tracking, and coil positioning guidance. The integrated coil positioning arm ensures stable, reproducible coil placement throughout long sessions — critical for studies requiring consistent stimulation of the same cortical target across multiple sessions or participants. A fully adjustable reclining research chair completes the setup, allowing subjects to be positioned comfortably for both upper and lower limb protocols.

Dr. Silvi Frenkel-Toledo's Lab: Decoding Motor Recovery Through Brain Stimulation

Dr. Silvi Frenkel-Toledo is a lecturer and researcher in the Department of Physiotherapy at Ariel University's Faculty of Health Sciences. Her lab sits at the intersection of clinical neuroscience and rehabilitation, exploring how the brain learns, adapts, and recovers motor function following stroke and neurological injury.

A central focus of the lab is the mirror neuron system and the role of action observation in driving motor learning — leveraging the brain's capacity to simulate observed movements as a therapeutic tool. This work has led to studies combining action observation with non-invasive brain stimulation: using HD-tDCS and TMS to selectively modulate the inferior parietal lobe and inferior frontal gyrus, the key nodes of the human mirror neuron network. Published research from the lab has demonstrated how targeted brain stimulation can enhance sensorimotor performance, improve cross-limb transfer of motor skills, and optimize the therapeutic effects of action observation in both healthy adults and stroke patients.

The Mag&More PowerMAG system enables the lab to perform precise single-pulse TMS for cortical mapping and MEP assessment, design rTMS protocols for motor cortex modulation, and combine TMS with behavioral and electrophysiological measures — bridging the gap between basic neuroscience and clinical physiotherapy practice.

Supporting Israeli Physiotherapy and Neurorehabilitation Research

The installation of the Mag&More PowerMAG at one of Israel's growing health science universities reflects the expanding role of TMS in physiotherapy research and clinical translation. As rehabilitation science increasingly turns to brain stimulation to accelerate and personalize recovery, having a research-grade TMS platform in a physiotherapy department bridges neuroscience and clinical practice in a uniquely powerful way. NBT is proud to support Dr. Frenkel-Toledo's research at Ariel University and looks forward to the discoveries that will emerge from this state-of-the-art brain stimulation lab.