MEA2100-Mini-Systems
Compact, scalable in vitro MEA recording system with 60/120-channel headstages, 24-bit resolution at 50 kHz/channel, and support for up to 8 parallel headstages for high-throughput electrophysiology.

Overview
The MEA2100-Mini-Systems is a compact, high-performance in vitro electrophysiology recording system designed for flexible and scalable neuronal and cardiac network studies. Each headstage offers 60 or 120 recording channels at 24-bit resolution and 50 kHz per channel, with 2 independent stimulation channels built in. For high-throughput applications, up to 8 headstages can be connected in parallel—enabling simultaneous acquisition of up to 480 or 960 channels across multiple preparations.
IFB-C Multiboot Interface Board
The MEA2100-Mini is powered by the new IFB-C Multiboot interface board, a next-generation platform compatible with MEA2100(-Mini), Multiwell-MEA, CMOS-MEA5000, ME2100, and W2100 headstages. It features real-time signal detection, a freely programmable DSP for custom processing pipelines, and SuperSpeed USB 3.0 connectivity for high-bandwidth data transfer.
System Setup
A complete MEA2100-Mini setup consists of Microelectrode Arrays (MEAs), a miniaturized headstage, a Signal Collector Unit (SCU), the IFB-C interface board, and a PC running Multi Channel Suite software. This modular architecture allows researchers to scale their recording capacity incrementally.
Headstage
The MEA2100-Mini headstage features a small footprint compatible with standard incubators, making it suitable for long-term recordings under physiological conditions. It supports 60 or 120 recording channels at 24-bit resolution, with 2 independent stimulation channels per headstage for closed-loop and stimulation-response protocols.
Signal Collector Unit (SCU)
Each Signal Collector Unit (SCU) supports up to 4 headstages, and two SCUs can be connected per IFB-C interface board—enabling control of up to 8 headstages simultaneously. The SCU also controls up to 4 optical stimulation units, supporting optogenetic experimental designs.
Software: Multi Channel Suite
The MEA2100-Mini integrates with Multi Channel Suite, a comprehensive software package including:
- Multi Channel Experimenter – Real-time data acquisition and experiment control
- Multi Channel Analyzer – Offline analysis with video synchronization capabilities
- Multi Channel DataManager – Data export to HDF5, Matlab, Python (.nex, .ced) formats
Expert Support
Multi Channel Systems provides PhD-level scientific support in neuronal and cardiac electrophysiology, Xenopus oocyte recordings, and Patch Clamp techniques. A dedicated sales and applications team is available for product demonstrations and on-site installation assistance.
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Electro-Physiology
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Academic publications and research studies utilizing Multi Channel Systems MEA technology, sourced from Google Scholar.
What is the MEA2100-Mini System and what is it used for?
The MEA2100-Mini is a compact, scalable in vitro multielectrode array (MEA) recording system from Multi Channel Systems. It supports 60/120-channel headstages with 24-bit resolution at up to 50 kHz per channel, enabling high-fidelity recording from neural and cardiac cell cultures.
What research applications is the MEA2100-Mini suited for?
The MEA2100-Mini is suited for in vitro electrophysiology, drug screening on neural and cardiac cultures, iPSC-derived cell characterization, network burst analysis, and any application requiring simultaneous multi-channel recording from MEA plates.
What are the key technical features of the MEA2100-Mini?
The MEA2100-Mini (catalog number: MEA2100-Mini) supports up to 8 parallel headstages for high-throughput applications, offers 24-bit ADC resolution, built-in signal conditioning, and real-time data processing. It is compatible with Multi Channel Systems' MC_Rack and MC_Experimenter software.
Is the MEA2100-Mini available in Israel with local support?
Yes. NBT Ltd is the exclusive distributor of Multi Channel Systems products in Israel. Our team provides installation, training, and ongoing technical support for the MEA2100-Mini and all MCS electrophysiology platforms.
What MEA substrates are compatible with the MEA2100-Mini?
The MEA2100-Mini is compatible with the full range of Multi Channel Systems MEA substrates, including standard 60-electrode, 120-electrode, and multiwell MEA formats. NBT Ltd can advise on the appropriate electrode layout and substrate coating for your specific cell type and application.
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