Simultaneous Electrophysiology and Optical Assessment

Incub8™ allows for optical and electrophysiological data in a single recording, giving researchers a more complete view of cellular events. This means cross-validation of results, stronger and more reliable conclusions, and improved predictive value for drug screening and mechanistic research. You’ll benefit from the temporal precision of MEA technology alongside the spatial resolution of live-cell imaging — in one experiment.

Better Data at a Lower Cost

Performing two assays at once saves time, samples, and reagents — streamlining your workflow without compromising quality.

• Reduced consumables and compound use
• Less hands-on time
• Accelerated timelines
• Lower overall costs

Stable Conditions, True-to-Life Data

Unlike other MEA systems, Incub8 records inside a humidified CO₂ incubator.

• No disruptions from moving plates in and out of controlled environments
• Reduced biological variability
• More reproducible, translatable results
• Fewer samples and replicates required

Ideal for: Safety & toxicity studies, Developmental biology, Circadian rhythm research, Sensitive cell models (e.g., iPSC-derived cells and organoids), and more.

Throughput Without Compromise

• 24- or 96-well plates available
• Connect up to 8 headstages simultaneously
• Record up to 768 samples at once

By testing all wells under identical conditions, you’ll gain higher reproducibility and better outcomes — while Incub8’s compact size allows for multiple headstages to fit inside an incubator.

Smarter Software, Stronger Science

Incub8-Screen Software is built for flexibility and regulatory-ready workflows:

• Easy to learn, supports standard & advanced protocols
• Automated signal analysis with derived parameters
• Barcode tracking for complete traceability
• Neuronal, cardiac, and compound screening modules included
• Programmable timer function for long-term experiments
• Online screening tool for data acquisition and automated signal analysis
• Offline analysis tool for in-depth data analysis and report generation

Designed for Flexibility

Set up Incub8 where you need it — inside an incubator, on the benchtop, or on upright or inverted microscopes. TTL-based integration makes it simple to sync with third-party devices for complex, multiparametric experiments.

Accessories

• Active Heating Plates & CO₂ Control Modules — maintain experimental conditions outside the incubator
• AccuTemp Stabilizer Plates — minimize temperature differences within the plate with <0.5°C temperature gradient
• Optimized Multiwell Plates — designed for seamless electrophysiology + optical assessment
• VariPlate Base Adapter — supports standard Multi Channel Systems MEA plates for added flexibility

FAQ

Can Incub8™ record electrophysiology and optical data at the same time?

Yes. Incub8™ uniquely supports simultaneous electrophysiology and optical assessment in a single recording session. This allows cross-validation of results, reduces the number of samples and replicates required, and combines the temporal precision of MEA technology with the spatial resolution of live-cell imaging — all in one experiment.

Why does recording inside a CO₂ incubator matter?

Recording from inside a humidified CO₂ incubator eliminates the disruption caused by moving plates in and out of controlled environments. This reduces biological variability, improves reproducibility, and delivers more translatable results — particularly for sensitive cell models such as iPSC-derived neurons, cardiomyocytes, and organoids.

How many samples can Incub8™ record simultaneously?

Incub8™ supports 24- or 96-well plates and up to 8 headstages connected simultaneously, enabling recordings from up to 768 samples at once. All wells are recorded under identical conditions, maximising reproducibility across the plate.

What software does Incub8™ use, and does it support regulatory workflows?

Incub8™ runs on the Incub8-Screen Software, which supports both standard and advanced protocols, automated signal analysis with derived parameters, barcode tracking for complete traceability, and neuronal, cardiac, and compound screening modules. It is designed to support regulatory-ready workflows for safety and toxicity studies.