What is the Elveflow OB1 MK4 Pressure Controller?

The OB1 MK4 is a state-of-the-art 4-channel microfluidic pressure and flow controller built around piezoelectric pressure regulators — the only technology of its kind on the market. Developed by Elveflow, a world leader in microfluidic instrumentation, the OB1 MK4 delivers pressure control that is 20 times more precise and 10 times faster than conventional alternatives, making it the instrument of choice for researchers who demand repeatability and fine temporal control in microfluidics experiments.

Each channel can be independently configured for positive pressure or vacuum, and can optionally be paired with Elveflow thermal (MFS) or Coriolis (BFS) flow sensors for closed-loop flow rate control of liquids and gases. The ESI software interface enables single-channel operation, multi-channel automation, and complex protocol sequencing — all from a single intuitive dashboard.

Key Features

• Piezoelectric pressure regulation: The OB1 MK4 is the only microfluidic controller worldwide to use piezoelectric regulators, delivering 20× greater precision and 10× faster response than solenoid-based competitors.
• Up to 4 independent channels: Configure each channel for pressure, vacuum, or both. Channels are upgradeable post-purchase to match evolving experimental needs.
• Wide pressure range: The OB1 MK4 supports pressure ranges from -900 mbar to 8 bar, with multiple range configurations available to suit low or high flow rate applications.
• Closed-loop flow control: Compatible with Elveflow MFS (thermal flow sensor) and BFS (Coriolis flow sensor) for real-time flow rate measurement and feedback control of both liquids and gases.
• ESI software: Elveflow’s Smart Interface (ESI) provides intuitive GUI-based control, programmable Sequencer for automated experimental protocols, and live data logging.
• Multi-platform communication: Supports USB and UART protocols for integration with Mac, Linux, Arduino, PLCs, and custom control environments via SDK.
• Upgradeable and modular: The OB1 MK4 can be expanded or reconfigured after purchase, protecting your investment as research needs evolve.