To study the subject’s interest in a social stimulus, one chamber presents a conspecific while the other remains empty. In a preference test for social novelty, the two wired cages contain a familiar and an unfamiliar conspecific. A third variation involves testing the social preference for two unfamiliar conspecifics. In most cases the interest is measured by assessing the time spent in the same chamber or in close proximity to the familiar or unfamiliar other mouse.
High-quality sociability cage
The Noldus sociability cage is especially designed for automated video tracking with EthoVision XT. It is made out of clear acrylic walls and is delivered with a white matted bottom and a dark matted bottom, making it suitable for tracking both light and dark colored mice.
The apparatus also includes two removable clear acrylic sliding doors to prevent access to the side chambers, and two small acrylic cages for the introduction of the unfamiliar (stranger) mice. A small space between the chambers allows you to slip a piece of paper inside in order to prevent visual contact between the three chambers.
Animal detection
EthoVision XT automatically detects and tracks the subject as it moves around the test arena. There is no need for sensors; EthoVision XT detects multi-colored animals such as hooded rats with ease. Advanced tracking technology and a wide range of detection methods to choose from will assure that you acquire highly accurate data.
Accurate detection of social contact
For precise detection of an animal’s location and position, EthoVision XT detects more than just a center point. We have developed a special algorithm for rodents that enables the additional detection of nose point and tail base. This offers great added value to social behavior studies. In a sociability test, the proximity to the wired cage can be narrowed down to the nose point of the test subject, providing more accuracy. Infrared backlight can improve contrast, making it easier to detect the animal.
EthoVision XT is used in over 10,000 publications. Get your free trial to try it out!