PEEK Inline Microfluidic Bubble Trap

Elveflow's redesigned Bubble Remover is an inline microfluidic bubble trap made from autoclavable PEEK (Polyetheretherketone). Developed in collaboration with engineers and researchers, it features a leak-proof design, PTFE microporous membrane, and optional vacuum-assisted operation for maximum bubble removal efficiency.

Working Principle

The bubble trap uses a microporous PTFE membrane (10 µm pores). As fluid flows through, gas bubbles are expelled through the hydrophobic membrane while aqueous liquid is retained — zero leakage. Operation is passive by default; a vacuum line can be added (e.g., from an OB1 MK4 vacuum outlet) for enhanced performance.

Key Benefits

• Autoclavable PEEK body — biocompatible and chemically resistant
• PTFE membrane — hydrophobic, 10 µm pores, easily replaceable between experiments
• Two operation modes: passive (no vacuum) or active (vacuum-assisted, up to 60 mL/min)
• Typical use range: 0.5–2.0 mL/min (passive); up to 60 mL/min with vacuum
• 3 internal volume options: 23 µL (S), 95 µL (M), 362 µL (L)
• Standard 1/4"-28 threaded ports — compatible with 1/32", 1/16", and 1/8" OD tubing
• Pressure rating: 2 bar (30 psi)
• Compact: 47 × 34 × 28 mm, L-shaped stable footprint

Applications

Recommended for any microfluidic experiment sensitive to air bubbles: cell perfusion, organ-on-chip systems, fluorescence imaging, flow cytometry, and any setup using a pressure controller as the fluid driver.

FAQ

Is the bubble trap autoclavable?

Yes. The PEEK body is autoclavable. You can also clean the bubble trap with distilled water after each experiment or with 70% ethanol for sterile work — remove the membrane before cleaning with ethanol, then flush with water to remove traces.

Can I use the bubble trap with organic solvents?

No. Organic solvents are not compatible with the bubble trap as they risk causing leakage.

How do I select the right size?

The three sizes (S: 23 µL, M: 95 µL, L: 362 µL) differ in internal volume. All sizes work across a wide range of flow rates (100 µL/min to 60 mL/min with vacuum). However, smaller internal volumes are less efficient at higher flow rates — choose the size based on your typical flow rate and experiment requirements.

Can I use vacuum to pull liquid through the trap?

No. You should always push liquid toward the trap inlet to avoid cavitation. Vacuum assistance (via the OB1 MK4 vacuum outlet) should only be applied to the vacuum port on the trap body, not to drive fluid through the system.

How often should I replace the membrane?

Membrane lifetime depends on the type of fluid used. Replace the membrane as soon as you observe a reduction in bubble removal efficiency. Two replacement membranes are included in the box.

What size tubing is compatible?

The threaded ports are standard 1/4"-28 fittings, compatible with 1/8", 1/16", and 1/32" OD tubing.