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MUX Quake Valve Controller by Elveflow
The MUX Quake Valve is a 16-valve 3:2 matrix dedicated to actuating bilayer PDMS Quake valves. With 20 ms switching, TTL trigger I/O, and ESI scheduler integration, it brings fast, precise, and fully programmable Quake-valve control to any PDMS-based microfluidic device when paired with an OB1 pressure controller.
What is the MUX Quake Valve Controller?
The MUX Quake Valve is Elveflow's flow switch matrix dedicated to actuating bilayer PDMS Quake-style microfluidic valves. With 16 3:2 valves in a single compact instrument, it lets you decide exactly when each PDMS valve is pressurised, automating the binary actuation patterns that define Quake-valve microfluidics. Fed by an OB1 MK3+ pressure controller, the system achieves 0.005% pressure stability — enabling fine valve position control and stable holding pressures across long experiments.
Key Features
- 16 × 3:2 valves: Compact matrix tailored to bilayer PDMS valve control.
- Fast switching: 20 ms valve actuation, with ROCKER® valve technology.
- Fine position tuning: When coupled with the OB1, achieves 0.005% pressure stability for precise PDMS valve hold pressures.
- Programmable sequences: Plug & play sequence editor — design, save, and loop complex actuation patterns.
- Trigger I/O: TTL trigger in/out for synchronisation with microscopes, shutters, or third-party instruments.
- Scalable: Control up to 256 valves by chaining several MUX Quake units.
- 10-32 PEEK fittings: Standard microfluidic compatibility.
Applications
The MUX Quake Valve is the natural choice for any workflow built around PDMS bilayer valves. Common applications include:
- On-chip peristaltic pumping with PDMS valve trios.
- Fast medium switching for drug testing and stimulation protocols.
- Sequential sample injection through PDMS multiplexers.
- Cell or particle sample screening on Quake-valve devices.
- Medium perfusion switch for cell biology under flow.
- Reagent switching in flow-chemistry chips.
- Diffusion studies with controlled on/off mixing zones.
- Unidirectional recirculation in organ-on-chip platforms.
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Technical Specifications
| Catalog Number | MUX-QUAKE |
| Valve type | 3-way solenoid valve |
| Number of valves | 16 |
| Response time | 10 ms (per valve) |
| Inlet / outlet connectors | 10-32 UNF |
| Number of inlets / outlets | 2 inlets / 16 outlets |
| Wetted materials | PEEK / FKM |
| Max supported pressure | 2.5 bar (36 psi) |
| Internal volume | 20 µL per valve chamber |
| Dimensions | 220 × 130 × 130 mm |
| Connection type | USB-B |
| Software & SDK | ESI, C++, Python, LabVIEW, MATLAB |
| Trigger | 1× TTL Trigger IN, 1× TTL Trigger OUT |
| Power supply | 100–240 VAC, 35 W |
Applications
- Bilayer PDMS / Quake valve actuation
- On-chip peristaltic pumping
- Sequential sample injection and multiplexing
- Fast medium switching for drug testing
- Cell perfusion in PDMS-based organ-on-chip devices
Microfluidics
Explore All ProductsElveflow Publications
Academic publications and research studies utilizing Elveflow microfluidic instruments, sourced from Google Scholar.
What is the MUX Quake Valve Controller and what is it used for?
The MUX Quake Valve is a 16-valve 3:2 matrix from Elveflow, dedicated to actuating bilayer PDMS Quake-style microfluidic valves. Paired with an OB1 pressure controller, it provides fast, programmable on/off control of Quake valves for on-chip peristaltic pumping, sample injection, and complex PDMS-based microfluidic workflows.
What research applications is the MUX Quake Valve Controller suited for?
The MUX Quake Valve is suited for on-chip peristaltic pumping, sequential sample injection, cell or particle screening, fast drug testing protocols, medium perfusion switching, reagent switching in flow chemistry, diffusion studies, and unidirectional recirculation on PDMS organ-on-chip devices.
What are the key technical features of the MUX Quake Valve Controller?
The MUX Quake Valve (catalog: MUX-QUAKE) integrates 16 × 3-way solenoid valves with 10 ms per-valve response time and 20 ms switching, supports up to 2.5 bar, uses 10-32 UNF PEEK fittings, and offers full ESI / SDK control (C++, Python, LabVIEW, MATLAB). Multiple MUX Quake units can be chained to control up to 256 valves.
Is the MUX Quake Valve Controller available in Israel with local support?
Yes. NBT Ltd distributes Elveflow microfluidic products in Israel. Our team provides local support and application guidance for the MUX Quake Valve and the complete Elveflow microfluidic automation ecosystem.
How does the MUX Quake Valve Controller integrate with Elveflow systems?
The MUX Quake Valve is designed to be fed by an Elveflow OB1 MK3+ or MK4 pressure controller, which delivers the 0.005% pressure stability required for fine PDMS valve hold pressures. All valve actuations are programmable through the ESI software sequencer alongside pressure setpoints, and TTL trigger I/O allows synchronisation with microscopes and third-party instruments.
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