The UMP3 (UltraMicroPump3) is WPI's precision microinjection syringe pump, designed to deliver or withdraw microliter-to-nanoliter volumes with exceptional accuracy and repeatability. Paired with the MICRO2T SMARTouch™ touchscreen controller, the UMP3 system is the standard choice for stereotaxic microinjections, cannulation drug delivery, intravitreal and intraocular injections, and microfluidic applications in neuroscience and life science research.

The UMP3 accepts a wide range of glass microsyringes from 0.5 µL to 1000 µL, including WPI’s NanoFil™ system, Hamilton, SGE, and ILS syringes (barrel diameters 5.5–9 mm). Using a 10 µL syringe, the system can deliver or withdraw as little as 25 nL per injection. The pump mounts directly to most stereotaxic frames and micromanipulators via a built-in mounting bar, and an optional foot switch enables hands-free recording of injection events.

The MICRO2T SMARTouch™ controller features a splash-proof touchscreen interface, dual-channel motor drive for simultaneous control of two UMP3 pumps, built-in memory for saving settings between sessions, and USB computer control for scripted protocols. A graphical display shows rate and volume remaining in the syringe in real time.

Patent-Pending SMARTouch™ Technology

Total system calibration: Calibrate the syringe and controller together as a system, eliminating syringe variability and ensuring the exact configured volume is delivered or withdrawn. Smart Smoothness: Automatically adjusts microstepping according to the injection rate for smooth, low-noise delivery. User-defined travel limits: Set custom drive limits on the MICRO2T to prevent the UMP3 from exceeding its range. End-stop detection dependent on syringe volume. Pause/Resume function for incremental dosing or sample collection during infusion or withdrawal.

Flexibility in Mounting and Configuration

The UMP3 mounts to any WPI micropositioner including the M3301 (manual) and DC3001 (motorized), as well as most stereotaxic manipulators. For retinal pigment epithelium (RPE) injections, the RPE-KIT mounts a NanoFil™ syringe on the UMP3 for accurate submicroliter injections. The controller is fully backward-compatible with all previous UMP3 models.

Applications

Stereotaxic microinjection in rodent and primate models. Cannulation and chronic drug delivery. Intravitreal injection (with RPE-KIT). Intraocular injection (with IO-KIT). Micro delivery of biochemical agents, dyes, and viral vectors. Accurate microinjection of solution into tissue. Microfluidic sample delivery and extraction. Precise control of nanoliter-to-milliliter volumes in life science research.

Available Configurations

UMP3 (Pump Only), UMP3T-1 (1 pump + MICRO2T SMARTouch™ controller), UMP3T-2 (2 pumps + MICRO2T controller), MICRO2T (SMARTouch™ Two-Channel Controller only). Computer control is available via USB on the rear of the MICRO2T. Note: glass syringes with barrel diameters from 5.5 to 9 mm are accepted; end-stop positions must be set on the MICRO2T before use.