Large Animal Stereotaxic Instruments

RWD Large Animal Stereotaxic Instruments are purpose-built for neuroscience research in cats, dogs, monkeys, and pigs, with an extended ±100 mm Y-axis range and support for up to six manipulator arms. Available in standard (100 μm) and digital (10 μm) resolution variants, these instruments provide the structural rigidity and precision required for complex large-animal surgical workflows.

Large Animal Stereotaxic Instruments

What are the Large Animal Stereotaxic Instruments?

The RWD Large Animal Stereotaxic Instruments are purpose-built for neuroscience research in cats, dogs, monkeys, pigs, and other large non-human subjects. Where standard rodent frames fall short, the large animal platform delivers the structural rigidity and extended range needed to precisely target deep brain structures in larger species. The instrument is available in both standard (100 μm) and digital (10 μm) resolution variants, and the modular multi-arm design supports up to six independent manipulator arms for complex, multi-site surgical workflows.

The Y-axis slide provides ±100 mm of linear travel (1 mm standard resolution, upgradeable to 50 μm with the optional AP Micro-driver), while X and Z axes maintain the same 80 mm working distance and 0.1 mm resolution as RWD’s rodent platform. A uniquely designed jaw plate system accommodates large animals ranging from under 10 kg (with the 68041 adaptor) to 10–30 kg (with the 68081 monkey adaptor), ensuring a stable, reproducible head-fixed position throughout lengthy surgical sessions.

Key Features

  • Multi-Species Platform: Interchangeable adaptors accommodate cats, dogs, monkeys, pigs, and other large animals in a range of body weights, making this a versatile frame for primate and large-animal research programs.
  • Extended Y-Axis Range (±100 mm): The Y-axis slide design provides a much longer anterior-posterior travel range than rodent frames, accommodating the longer skulls of large animals. Optional AP Micro-driver upgrades Y-axis resolution to 50 μm.
  • Dual Resolution Models: Choose between the standard model (100 μm, models 68813/68814) for routine procedures, or the digital display model (10 μm, models 68815/68816) for high-precision targeting applications.
  • Up to Six Manipulator Arms: The large base accommodates up to six independent manipulator arms for simultaneous multi-site injection, recording, or stimulation.
  • Unique Jaw Plate Design: A specialized jaw plate mechanism provides superior stability for heavy large-animal heads compared to standard ear bar approaches, maintaining fixation throughout extended surgeries.
  • Dual-Lead Screws: Consistent with RWD’s standard platform, dual-lead screws on all axes ensure smooth, stable manipulation with minimal backlash.
  • Full Angle Rotation: 180° vertical and 360° horizontal rotation on all manipulator arms, lockable at any angle for angled approach trajectories.

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Technical Specifications

Standard Model Resolution (X/Z)0.1 mm (100 μm)
Digital Model Resolution (X/Z)0.01 mm (10 μm)
Y-Axis Range±100 mm, 1 mm resolution (upgradeable to 50 μm with AP Micro-driver)
X/Z Working Distance80 mm per axis
Vertical Rotation180°, lockable at any angle
Horizontal Rotation360°, lockable at any angle
Max Manipulator ArmsUp to 6 independent arms
Lead Screw DesignDual-lead screws for enhanced stability
Animal Weight Range (68041 adaptor)Below 10 kg (dogs, cats, small primates)
Animal Weight Range (68081 adaptor)10–30 kg (monkeys, large primates)
Compatible SpeciesDogs, cats, monkeys, pigs, and other large animals

Order Information

Cat. No.Description
68813Stereotaxic for Large Animals, SGL M — Standard, 100μm accuracy, includes 68868N base and 68941 2-axis manipulator-left
68814Stereotaxic for Large Animals, Dual M — Standard, 100μm accuracy, includes 68868N base with left and right 2-axis manipulators
68815Stereotaxic for Large Animals, SGL M, Digital — 10μm accuracy with digital display, includes 68868N base and 68944 digital manipulator-left
68816Stereotaxic for Large Animals, Dual M, Digital — 10μm accuracy with digital display, includes 68868N base with left and right digital manipulators
68041Large Animal Adaptor (for animals below 10 kg)
68081Monkey Adaptor (for animals 10–30 kg)

Applications

  • Stereotaxic neurosurgery in non-human primates (NHP) and large rodents
  • Deep brain stimulation (DBS) electrode implantation in large animals
  • Viral vector injection into large-animal brain regions
  • Multi-site electrophysiology recording setups
  • Translational neuroscience research requiring large-animal models

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Peer-reviewed research using RWD Large Animal Stereotaxic Instruments

RWD Large Animal Stereotaxic Instruments support translational neuroscience research in non-human primates, dogs, cats, and pigs. These instruments have been used in studies investigating deep brain stimulation, primate cortical mapping, large-animal models of neurological disease, and multi-site electrophysiological recording.

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