Key Features of the VF-510-0Z Vibratome
Key Features of the VF-510-0Z Vibratome

A. Durable: Equipped with a powerful, cordless motor for quiet and durable operation
B. Compact design: A fraction of the size of a legacy Vibratome, the Compresstome can easily fit into a hood, and takes much less space on your bench
C. Fast loading of cutting samples: Our one-touch unlocking mechanism on the sliding control box allows for rapid sample loading
D. User-friendly controls: Fully integrated control box has intuitive control parameters for controlling tissue sectioning

E. Increased lifespan of microtome: Built-in see-through cover protects oscillating parts from aerosolized buffer solution
F. Compatible with multiple blade types: New magnetic blade holder allows for easy magnetic attachment of stainless steel blades, or glue-on attachment of ceramic and tungsten blades
G. Easy to clean: Removable buffer tray and tube base allow for easy cleaning and changing tube sizes
The VF-510-0Z Excels Where Legacy Vibratomes Fall Short
At Precisionary, we know what gets in the way of your science. That’s why we offer industry-leading, reliable workhorse vibratomes backed by responsive expert support.
Consistent Cell Viability
In a legacy vibratome, tissues are not well supported when slicing, causing the sample to be pushed and squished, which can lead to damaged cells and altered tissue architecture. The VF-510-0Z’s fast slicing technique preserves cell viability, making it ideal for live tissue experiments like ephys, ensuring cells remain functional and intact.
Service & Maintenance
For many instrument manufacturers, vibratomes are just another product line. At Precisionary, tissue sectioning is our main focus. Our scientists and technical engineers are always available to answer your questions or assist you in troubleshooting to achieve your desired results.
Product Reliability
Traditional manufacturers typically offer a 1-year warranty and optional service plans. Backed by a 5-year warranty, the VF-510-0Z offers long-term reliability, giving users peace of mind that the product is built to last.
The VF-510-0Z Compresstome® is designed to be the most consistent and reliable vibrating microtome on the market.
Get a 360-degree view of this cutting-edge instrument, and explore key features below:
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Tissue Slicing
Explore All ProductsPublications using the Compresstome technique
Academic publications utilizing the Compresstome vibrating microtome technique for precision tissue slicing, sourced from Google Scholar.
What tissue types can be sectioned with the Compresstome VF-510-0Z?
The Compresstome VF-510-0Z produces high-quality sections from unfixed or lightly fixed brain, spinal cord, retina, liver, and other soft tissues, maintaining cell viability for acute slice electrophysiology, immunohistochemistry, and live imaging.
What section thickness range does the Compresstome VF-510-0Z support?
It supports section thicknesses from approximately 20 µm to several millimeters with precise micrometer-level repeatability, covering both acute brain slices at 300–400 µm and thin sections for confocal and super-resolution imaging.
Is the Compresstome VF-510-0Z suitable for acute brain slice electrophysiology?
Yes. The agarose embedding and compression system minimizes tissue deformation and cellular damage during vibration-based cutting, producing slices with excellent viability widely used in patch-clamp studies of synaptic physiology.
How does the Compresstome VF-510-0Z differ from traditional vibratomes?
Unlike conventional vibratomes, the Compresstome uses a proprietary compression syringe that stabilizes the tissue block with agarose, reducing vibration artifacts and yielding more consistent section quality across the entire slice. NBT Ltd supports Compresstome in Israel.
What are the key advantages of the VF-510-0Z over the VF-210-0Z Compresstome model?
The Compresstome VF-510-0Z features enhanced vibration control and a larger bath capacity compared to the VF-210-0Z, making it better suited for higher-throughput slicing and for larger tissue samples. Both models share the same agarose compression tube technology, with the VF-510-0Z offering additional capacity and precision for labs requiring consistent slices across multiple experiments per session.
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