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Peri-Star Pro Peristaltic Pump
The WPI Peri-Star Pro is an affordable, high-performance digital peristaltic pump covering 0.1–280 mL/min across 2, 4, or 8-channel configurations. With 0.5% flow accuracy, planetary gear-driven low-pulsation rollers, and built-in self-calibration, it is the standard choice for brain slice perfusion, organ perfusion, and cell culture under flow in neuroscience and cell biology labs.
What is the WPI Peri-Star Pro Peristaltic Pump?
The WPI Peri-Star Pro (PERIPRO series) is an affordable, high-performance digital peristaltic pump designed for continuous, pulse-minimized fluid delivery in laboratory settings. Operating across a wide flow range of 0.1 to 280 mL/min, the Peri-Star Pro is the go-to perfusion pump for brain slice electrophysiology, cell culture under flow, organ perfusion, and microfluidics applications where consistent, contamination-free fluid delivery is essential.
Available in 2, 4, or 8-channel configurations in both high-rate and low-rate versions, the PERIPRO series covers the full spectrum of laboratory perfusion tasks — from slow, precision drug delivery to high-throughput media exchange — all controlled via an intuitive backlit LCD interface with built-in self-calibration.
Key Features
- Wide Flow Range (0.1–280 mL/min): The low-rate models (PERIPRO-4LS, PERIPRO-8LS) cover 0.1–80 mL/min ideal for ACSF perfusion, patch clamp slice prep, and microfluidics; the high-rate models (PERIPRO-2HS, PERIPRO-4HS) extend to 280 mL/min for larger-scale organ perfusion and media recirculation.
- 0.5% Flow Rate Accuracy: Planetary gear-driven rollers and a built-in self-calibration function achieve 0.5% flow accuracy — ensuring reproducible perfusion rates critical for pharmacological experiments and dose-response measurements.
- Dual Operating Modes: Run in flow rate mode (mL/min) or rotation speed mode (rpm, 0.1 RPM resolution in remote mode), with bidirectional rotation for withdrawal or recirculation setups.
- Planetary Gear Rollers for Minimal Pulsation: The unique planetary gear design actively drives all rollers (8 for low-rate, 4 for high-rate), ensuring smooth, low-pulsation flow that protects sensitive preparations from mechanical disturbance.
- Backlit LCD with Water-Resistant Keypad: The large backlit display simultaneously shows rotation direction, flow rate or RPM, tubing ID, drive status, and remote mode. The membrane keypad protects electronics from liquid splashes during routine lab use.
- Snap-On Tubing Cartridges: Tubing is replaced in seconds using snap-on cartridges without tools, minimizing cross-contamination risk between experiments. Compatible with tubing IDs from 0.5 mm to 6.4 mm (depending on model).
- Built-In HMI with On-Screen Guidance: Plain-English screen instructions walk users through setup, calibration, and operation — reducing the learning curve and the need to refer to the manual.
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Choosing Your Model
The Peri-Star Pro family offers four configurations to match your flow requirements and number of channels:
| PERIPRO-2HS | 2 channels, high rate (0.8–280 mL/min), 3.1–6.4 mm ID tubing |
| PERIPRO-4HS | 4 channels, high rate (0.8–280 mL/min), 3.1–6.4 mm ID tubing |
| PERIPRO-4LS | 4 channels, low rate (0.1–80 mL/min), 0.5–2.4 mm ID tubing |
| PERIPRO-8LS | 8 channels, low rate (0.1–80 mL/min), 0.5–2.4 mm ID tubing |
For most neuroscience applications (brain slice perfusion, patch clamp setups), the PERIPRO-4LS or PERIPRO-8LS are recommended — they cover ACSF flow rates (1–10 mL/min) with fine control and low pulsation. High-rate models are suited for tissue perfusion, drug loading, or recirculation systems requiring higher volumes.
Typical Laboratory Applications
- Brain Slice Electrophysiology: Deliver continuous ACSF flow (2–10 mL/min) over acute brain slices during whole-cell, sharp electrode, or field potential recordings. The low-pulsation design preserves slice health and recording stability.
- Organ Perfusion: Perfuse isolated hearts, kidneys, or other ex vivo tissue preparations with oxygenated physiological buffer at controlled rates.
- Cell Culture Under Flow: Drive laminar flow through ibidi µ-slides and other microfluidic culture chambers to apply defined shear stress to endothelial or epithelial cells.
- Drug Delivery and Pharmacology: Switch between drug-containing and control solutions via multi-channel operation, with precise flow rates for dose-response experiments.
- Microfluidics: Pump through microfluidic chips, dialysis tubing, or miniaturized organ-on-a-chip platforms requiring stable, low-volume flow.
Technical Specifications
| Parameter | Low Rate (PERIPRO-4LS / 8LS) | High Rate (PERIPRO-2HS / 4HS) |
| Number of channels | 4 or 8 | 2 or 4 |
| Number of rollers | 8 | 4 |
| Flow range | 0.1–80 mL/min | 0.8–280 mL/min |
| Tubing ID range | 0.5–2.4 mm | 3.1–6.4 mm |
| Supplied tubing | #14 (0.2–18 mL/min) | #17 (3.5–280 mL/min) |
| Rotor speed range | 1–100 RPM | |
| Speed resolution | 1.0 RPM (normal); 0.1 RPM (remote) | |
| Flow rate accuracy | 0.5% (with self-calibration) | |
| Rotation | Clockwise and counter-clockwise | |
| Self-calibration | Yes (on-screen guided) | |
| Display | Large backlit LCD | |
| Working temperature | 0–45°C | |
| Humidity | < 80% non-condensing | |
| Power | 110–220 VAC, 50–60 Hz; Fuse 1A 250V | |
| Dimensions | 190 × 162 × 275 mm | |
| Shipping weight | 11 lb. (5 kg) | |
Applications
- Brain slice perfusion (ACSF delivery) during electrophysiology recordings
- Organ and tissue perfusion with oxygenated physiological buffer
- Cell culture under flow (shear stress experiments with microfluidic chambers)
- Microfluidic drug delivery and pharmacological solution switching
- Recirculation perfusion systems for extended ex vivo preparations
Peri-Star Pro Peristaltic Pump Publications
Peristaltic pumps including the WPI Peri-Star Pro series are widely cited in neuroscience and cell biology research for maintaining continuous perfusion of artificial cerebrospinal fluid (ACSF) in brain slice electrophysiology, driving microfluidic flow in organ-on-a-chip setups, and delivering controlled media flow to cultured cells. Their accuracy and low pulsation make them a preferred choice for preparations requiring stable flow conditions.
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