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Operon
Multi-modal operant conditioning chamber for testing cognitive flexibility in rodents (Papaleo–Scheggia's method). Features a 6-texture revolving floor, 10-channel odor delivery system, and dual nose poke sensors; available for mice (49500) and rats (49503); dimensions 30×60×55 cm.
Operon
The Operon by Ugo Basile (Papaleo–Scheggia's method) is a sophisticated multi-modal operant conditioning chamber designed for testing cognitive flexibility and executive function in rodents. Combining a 6-texture revolving floor, a 10-channel olfactory delivery system, and dual nose poke sensors, the Operon enables complex rule-based and reversal-learning paradigms in a single, automated apparatus.
With overall dimensions of 30 × 60 × 55 cm, the system is available for both mice (Cat. 49500) and rats (Cat. 49503), and integrates seamlessly with standard operant software for fully automated data collection and analysis.
Key Features
- 6-texture revolving floor for tactile discrimination tasks
- 10-channel odor delivery system
- Dual nose poke sensors for operant responding
- Available in mouse (49500) and rat (49503) versions
- Dimensions: 30 × 60 × 55 cm
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Research Applications
The Operon system, developed following Papaleo–Scheggia's method, is specifically designed to study cognitive flexibility and executive function — cognitive domains critically impaired in schizophrenia, OCD, and other psychiatric disorders. Its multi-modal sensory approach enables rich, multi-dimensional behavioral phenotyping.
- Cognitive flexibility: Assessing reversal learning and attentional set-shifting
- Schizophrenia models: Studying executive function deficits and their pharmacological remediation
- Olfactory discrimination: Leveraging the 10-channel odor system for olfactory-based learning tasks
- Tactile discrimination: Using the 6-texture floor for texture-based rule learning
- Drug discovery: Screening cognitive enhancers and antipsychotics in rodent models
Memory and Learning
Explore All ProductsWhat is the Operon designed to test?
The Operon tests cognitive flexibility and executive function through complex multi-sensory discrimination and reversal-learning tasks, following Papaleo–Scheggia's validated behavioral method.
What sensory modalities does the Operon support?
The Operon integrates three sensory modalities: tactile (6-texture revolving floor), olfactory (10-channel odor delivery), and operant response (dual nose poke sensors).
Are both mice and rat versions available?
Yes. Cat. 49500 is the mouse version and Cat. 49503 is the rat version of the Operon system.
What are the dimensions of the Operon?
The Operon measures 30×60×55 cm, providing a compact yet fully equipped testing environment for complex cognitive tasks.
What psychiatric disorders does the Operon help model?
The Operon is particularly relevant for modeling cognitive deficits seen in schizophrenia and OCD, where reversal learning and cognitive flexibility are characteristically impaired.
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