The MEA2100-System is the most versatile in vitro recording system from Multi Channel Systems. You can record from neuronal or cardiac cultures, stem cells, or brain or cardiac slices.

It is based on an idea from the 1970’s, when Thomas et al. found that electrical activity can be recorded extracellularly with microelectrode arrays (MEA). Over the decades, many peer-reviewed articles have proven that the MEA technology is indeed a very powerful tool in electrophysiology research and the technology around the MEA has improved significantly.

Today, the MEA2100-System is a very compact solution with integrated amplifier and stimulus generator, temperature control, and the option for real-time signal detection and feedback.

The main advantage of the MEA2100-System is its flexibility. Various headstage types facilitate the usage of different MEAs. You can record from up to 4 MEAs in parallel, all at a sampling rate of 50 kHz per channel, ensuring an excellent data quality.

MCS-IFB 3.0 Multiboot

As part of the system, the MCS-IFB 3.0 Multiboot is a new interface board generation which is able to receive data from a MEA2100(-Mini)-Headstage, a Multiwell-MEA-Headstage, a CMOS-MEA5000-Headstage, a MEA2100-Beta-Screen-Headstage, a MCS-SCU or a W2100-Receiver. This makes cost-effective combinations with only one interface board and multiple recording systems possible. You can establish for example your experiments on 60, 120, or 256 electrodes with the MEA2100-System, then add the Multiwell-MEA-Headstage and start high-throughput screening. It’s also possible to use the same interface board for in vitro MEA experiments and tethered / wireless in vivorecordings. This leaves you with even more flexibility in switching between possible configurations for your specific research needs.



Key features:

  • Real-time signal detection and feedback*
  • Freely programmable DSP*
  • Multiple inputs/outputs, including digital, analog, and audio
  • SuperSpeed USB 3.0 ports

* applicable for MEA2100(-Mini), ME2100, and W2100

The main benefits of the MEA2100-System are:

  • Versatile system for a variety of applications
  • Very flexible because of different headstage types and possibility to connect two headstages to one interface board
  • Stimulation integrated in MEA-headstage (current and voltage)
  • Recording and stimulation controlled from within one software
  • Large variety of microelectrode arrays
  • Real-time signal detection and feedback possible
  • Powerful and flexible software Multi Channel Suite with unlimited upgrades included



mcs logo mit slogan blau e1554576489497

Publications using the MEA2100

Request for Quote

Please fill in as much details as possible and we will take care of your request as soon as possible

*Required field