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Treadmill for Mice and Rats
The Ugo Basile Treadmill (Cat. 47300) is a precision exercise platform for assessing endurance, motor performance, and physiological responses in both mice and rats. Featuring interchangeable lane assemblies, a 4.3-inch touchscreen, adjustable speed (3–100 m/min), and inclination (−25° to +25°), it supports a wide range of acute and chronic exercise study designs with optional air-puff or mild-shock motivational stimuli.
What is the Ugo Basile Treadmill?
The Ugo Basile Treadmill – Interchangeable Lane Assembly (catalog numbers 47300/47350) is a precision motorised rodent treadmill designed for measuring exercise endurance, distance, and speed in mice and rats. The system features interchangeable lane assemblies that allow the same unit to switch between mouse and rat configurations without additional hardware, making it an exceptionally cost-effective platform for multi-species laboratories.
Equipped with a 4.3-inch resistive touch screen and the XPad PC software suite, the treadmill supports three operating modes — constant speed, accelerating ramp, and fully custom ramps — as well as an adjustable inclination from −25° to +25°. An integrated shock grid provides an aversive motivational stimulus when required.
Key Features
- Interchangeable Lane Assembly: A single treadmill unit accepts both mouse and rat lane assemblies, eliminating the need to purchase separate instruments for each species.
- Speed Range 3–100 m/min: Wide-range speed control with 1 m/min precision supports protocols from low-intensity endurance walking to maximal sprint assessments.
- Adjustable Inclination (−25° to +25°): Variable incline enables uphill and downhill exercise protocols for metabolic, cardiovascular, and fatigue research.
- Integrated Shock Grid: Optional aversive stimulus (0–2 mA, 0.1 mA steps, 1–3 Hz) motivates animals without manual intervention.
- Touch-Screen & XPad Software: Custom ramp and interval protocols are built visually in XPad and executed directly from the device display.
- Automatic Data Capture: Endurance, distance, speed, and shock events are recorded automatically and exported to CSV.
- Air Puff Option (47350): An air puff motivational system is available as an alternative to the shock grid for protocols requiring non-aversive stimulation.
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Research Applications
The Ugo Basile Treadmill is used across a broad range of disciplines where forced locomotion at controlled speed and incline is needed as either an experimental endpoint or an intervention. Its programmable ramp protocols allow researchers to implement standardised maximal oxygen consumption (VO₂max) tests, fatigue-to-exhaustion protocols, or chronic moderate exercise interventions with high reproducibility.
- Exercise Physiology & Metabolic Research: Standardised treadmill protocols measure aerobic capacity, endurance, and metabolic responses (VO₂max, lactate threshold) in normal and obese/diabetic rodent models.
- Cardiovascular Research: Cardiac hypertrophy, heart failure models, and hypertension are characterised with treadmill endurance capacity as a non-invasive functional endpoint.
- Neurorehabilitation: Treadmill training is used as a therapeutic intervention in spinal cord injury and stroke models to promote motor circuit reorganisation and recovery.
- Neuropathic Pain: Voluntary and forced treadmill activity are contrasted to quantify pain-related reductions in exercise motivation and gait quality.
- Drug & Gene Therapy Screening: Treadmill endurance and performance metrics serve as sensitive outcome measures in preclinical efficacy studies for muscle disease, metabolic syndrome, and mitochondrial disorders.
- Aging & Frailty: Age-related declines in treadmill performance are well-characterised, making the device a standard tool for longitudinal aging studies and anti-aging intervention screening.
Technical Specifications
| Catalog Numbers | 47300 (standard) / 47350 (air puff) |
| Speed Range | 3–100 m/min (1 m/min increments) |
| Slope Range | −25° to +25° (5° increments) |
| Operating Modes | Constant, accelerating ramp, custom ramp |
| Shock Stimulus | 0–2 mA, 0.1 mA steps, 1–3 Hz |
| Touch Screen | 4.3-inch resistive |
| Software | XPad |
| Power Requirement | 100–240 VAC, 50–60 Hz, 150 W max |
| Sound Level | ~80 dB at max speed |
| Operating Temperature | 10–40°C |
| Total Weight | 27 kg |
| Dimensions (W × D × H) | 56 × 67 × 35 cm |
| Warranty | 12 months + 12 months upon registration |
Applications
- Exercise endurance and VO₂max assessment
- Cardiovascular and metabolic research
- Neurorehabilitation protocols (spinal cord injury, stroke)
- Neuropathic pain exercise motivation studies
- Drug and gene therapy efficacy screening
- Aging and frailty research
Motor Functions
Explore All ProductsTreadmill Exercise Research Publications
The Ugo Basile Treadmill is widely cited in exercise physiology and behavioral studies involving mice and rats. Research covers aerobic exercise effects on muscle atrophy, inflammation, cardiac regeneration, and drug interventions, with the interchangeable lane assembly enabling flexible speed, inclination, and species configurations.
What is the Ugo Basile Treadmill and what is it used for?
The Ugo Basile Treadmill (Cat. 47300) is used to study behavioral, physiological, biochemical, and molecular responses to acute and chronic exercise in mice and rats. It measures endurance, distance, speed, and response to exercise stress in preclinical models of muscle atrophy, metabolic disease, cardiac function, and motor rehabilitation.
What speed and inclination ranges does the Treadmill support?
The Treadmill supports speeds from 3 to 100 m/min (1 m/min increments) and inclinations from −25° to +25° (5° steps). This flexibility enables both gentle forced-walking protocols and intensive endurance challenges within a single instrument.
Does the Treadmill include motivational stimuli, and are they adjustable?
Yes. The Treadmill includes a mild electric shock grid (0–2 mA, 0.1 mA steps, 1–3 Hz) and an optional air-puff stimulus (Cat. 47350-005). Both are adjustable in intensity, allowing researchers to select the most appropriate motivational method for their model.
Is the Treadmill available in Israel with local support?
Yes. NBT Ltd is the exclusive distributor of Ugo Basile products in Israel and provides full local support including system setup, protocol training, and ongoing technical assistance.
Can the Treadmill run mice and rats, and how many animals can be tested simultaneously?
Yes. The Treadmill uses interchangeable lane assemblies — six lanes for mice or three lanes for rats. Mouse and rat assemblies cannot be mixed in a single session, but changing the assembly is quick. Up to six mice or three rats can be tested simultaneously.
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