R550 Multi-Output Anesthesia Machine

Wall-mountable RWD anesthesia machine that anesthetizes 1–5 small animals simultaneously, with independent ON/OFF control per mask output and a separate induction chamber line. The high-throughput choice for rodent stereotaxic surgery cohorts and multi-animal physiology recordings. Available with isoflurane (R550IE) or sevoflurane (R550SE) vaporizers.

R550 Multi-Output Anesthesia Machine

What is the R550 Multi-Output Anesthesia Machine?

The R550 from RWD Life Science is a multi-output, wall-mountable laboratory anesthesia machine purpose-built to deliver inhalation anesthesia to 1–5 small animals simultaneously — mice, rats, hamsters, guinea pigs, rabbits and cats up to 7 kg. Each of the five mask outputs has its own independent ON/OFF toggle, so animals can be added, removed or re-positioned mid-protocol without disturbing the others. A separate induction chamber line with its own 0–2.0 L/min flowmeter lets the technician prep the next subject while a procedure is underway.

The R550 is the workhorse anesthesia bench for high-throughput rodent surgery suites, multi-animal physiology recordings, and any pipeline where serial animals need anesthesia and recovery in the same session.

Key Features

  • 5 mask outputs + 1 induction chamber: Anesthetize up to five small animals simultaneously, with the induction chamber gas flow controlled on a separate line.
  • Independent per-channel ON/OFF: Each mask output is its own toggle switch — service one animal without disturbing the others.
  • Independent dual flowmeters: 0–4 L/min for the vaporizer manifold and 0–2.0 L/min for the induction chamber.
  • High-accuracy vaporizer: Individually tested with its own report; isoflurane (0–5%) or sevoflurane (0–8%), Easy Fill or Key Fill options.
  • Long-life toggles: Gas path switches rated for 100,000+ cycles.
  • 10 L/min O₂ flush: Clears residual anesthetic from tubing or induction chamber on demand.
  • Flexible gas supply: Operate on oxygen or air; upgradable to portable configuration.

Why multi-output anesthesia matters for throughput

Most modern rodent surgery pipelines (stereotaxic injections, neural implantation, behavioral surgery cohorts) require anesthetizing multiple animals per session. A single-channel anesthesia bench forces serial induction — the throughput-limiting step on the day. A multi-output system like the R550 lets a research group induce and maintain anesthesia on as many as five animals simultaneously, with a dedicated induction chamber for the next subject in queue.

The R550’s independent per-channel control matters operationally: an animal that reaches surgical depth can be moved to its surgical platform, its channel turned off, and the next animal swapped in — without interrupting anesthesia on the other four masks. The result is shorter procedure days, more reproducible inter-animal anesthesia duration, and fewer awake-animal welfare events.

Typical Use Cases

  • Rodent stereotaxic surgery cohorts (AAV injection, electrode implantation, fiber implantation).
  • Multi-animal physiology recording suites under inhalation anesthesia.
  • Drug administration and tissue collection studies requiring batched anesthesia.
  • Veterinary teaching labs where multiple stations operate simultaneously.

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Models

R550IEEnhanced Multi-Output Anesthesia Device — Isoflurane, Easy Fill, 0–4 L. Includes connection tubing for mask & induction chamber.
R550SEEnhanced Multi-Output Anesthesia Device — Sevoflurane, Easy Fill, 0–4 L.

Technical Specifications

Outputs1 induction chamber + up to 5 masks (simultaneous)
Compatible AnimalsRats, mice, hamsters, guinea pigs, rabbits, cats (≤ 7 kg)
Vaporizer Flowmeter0–4 L/min O₂
Induction Chamber Flowmeter0–2.0 L/min (independent)
O₂ Flush10 L/min push-button
Isoflurane Range0–5% (Easy Fill or Key Fill)
Sevoflurane Range0–8%
Concentration Accuracy< 10%
Toggle Lifespan100,000+ switching cycles
Operating Temperature10–35 °C
Gas SupplyOxygen or air

Applications

  • High-throughput rodent stereotaxic surgery
  • Multi-animal in-vivo physiology recordings
  • Batched drug administration studies
  • Teaching and training labs

R550 multi-output anesthesia machine front view
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Peer-reviewed research using the RWD R550 multi-output anesthesia machine

The R550 is widely cited in high-throughput rodent surgery and physiology workflows where multiple animals must be anesthetized simultaneously. Typical studies describe stereotaxic injection cohorts, multi-animal imaging, and batched pharmacology protocols.

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