Plethysmometer
The Plethysmometer measures small changes in rodent paw volume and oedema to quantify the inflammatory response. With hands-free operation, 0.01 ml resolution, and a 4.3-inch colour touchscreen, it is the standard tool for anti-inflammatory drug screening.

The Plethysmometer measures small changes in volume and oedema (fluid retention) to gauge the inflammatory response, suitable for anti-inflammatory screening tests. It provides hands-free precision operation, detecting and displaying 0.01 ml changes in rodent paw volume with easy data transfer and included software.

Research Applications
The Plethysmometer is the standard method for quantifying paw oedema as a measure of the inflammatory response in rodent models. It is widely used in anti-inflammatory drug screening, carrageenan-induced paw swelling studies, and models of arthritis and chronic inflammation to track oedema progression and drug-mediated resolution over time.
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Analgesia
Explore All ProductsPlethysmometer Publications
The Ugo Basile Plethysmometer (Cat. 37240) has over 3,000 publications and is the gold standard for measuring paw volume and oedema in anti-inflammatory drug screening. It detects 0.01 ml changes in rodent paw volume to assess carrageenan-induced and other inflammatory oedema models.
What does the Plethysmometer measure?
The Plethysmometer measures rodent paw volume via fluid displacement with 0.01 ml resolution, to quantify oedema as a marker of inflammation.
What cell sizes are available?
Three versions are available: 37240 (standard), 37240-25 (25 ml cell), and 37240-35 (35 ml cell) to accommodate different rodent sizes.
How is data recorded?
Data is displayed on a 4.3-inch colour touch-screen and exported in 4-digit, 2-decimal format (e.g., 23.89 ml).
Is the Plethysmometer hands-free?
Yes, the operator places the animal's paw in the cell and the instrument records the volume change automatically, without requiring manual input.
What is the warranty?
12 months standard warranty, extendable to 24 months upon product registration.
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