Plantar Test (Hargreaves Apparatus)

The Plantar Test (Hargreaves Apparatus) is the gold standard for thermal hyperalgesia assessment in unrestrained rodents, with over 2,600 scientific publications. Automated focused infrared stimulation through a glass pane enables precise measurement of paw withdrawal latency.

Plantar Test (Hargreaves Apparatus)

In the late 1980s Dr. Hargreaves invented a method to assess thermal pain sensation in unrestrained rodents by stimulating the single hind paw, allowing for unilateral and contralateral experiments. Ugo Basile’s automated instrument applies focused infrared light through a glass pane to measure paw withdrawal response — now the gold standard with over 2,600 publications.

Research Applications

The Plantar Test (Hargreaves method) is the gold standard for evaluating thermal hyperalgesia in rodent models of inflammatory and neuropathic pain. With over 2,600 publications, it is used to assess analgesic drug efficacy, phenotype genetic models, and study mechanisms of central and peripheral sensitization in unilateral and bilateral pain paradigms.

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CategorySpecification
Command Input4.3" touch-screen
Power Requirements100–240 VAC, 50–60 Hz, 50 W
Sound Level<54 dB
Operating Temperature10–40°C, 5–95% RH
IR IntensityAdjustable 01–99
Latency Time0.1 s steps
Cut-off Function5–30 seconds
Measurement ModeManual or Automatic
Data Export.csv format
Dimensions135(w) × 40(d) × 50(h) cm
Weight11 kg
Mouse Enclosure96 × 96 × 140 mm (max 12 animals)
Rat Enclosure96 × 196 × 140 mm (max 6 animals)
Warranty12 months + 12 months post-registration

Peer-reviewed research using the Ugo Basile Plantar Test (Hargreaves Apparatus)

The Ugo Basile Plantar Test (Cat. 37570, Hargreaves apparatus) has over 2,600 publications citing it for thermal hyperalgesia assessment in unrestrained rodents. It measures infrared heat-induced paw withdrawal latency in inflammatory and neuropathic pain models, enabling unilateral/contralateral comparisons.

How many animals can be tested simultaneously?

Up to 12 mice (in 96×96×140 mm enclosures) or 6 rats (in 96×196×140 mm enclosures) can be tested simultaneously.

What is the cut-off time function?

The cut-off function is adjustable from 5 to 30 seconds to protect animals from tissue damage in case of no response.

What is the IR intensity range?

IR intensity is adjustable from 01 to 99 in single steps, providing precise control over the thermal stimulus applied to the paw.

Can the Plantar Test be used for both mice and rats?

Yes, the Plantar Test is designed for both mice and rats, with species-specific modular enclosures available.

What is the warranty?

12 months standard warranty, extendable to 24 months upon product registration.

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