.svg)
.svg)
PAM Pressure Application Measurement
The PAM (Pressure Application Measurement) is designed for measuring mechanical pain threshold on joints, specifically validated for arthritis research. It assesses joint hypersensitivity in rodent knees and ankles with two force ranges (0–500 and 0–1,500 gf).
The P.A.M. (Pressure Application Measurement) is an original tool designed for measuring mechanical pain threshold on joints. Specifically designed and validated for arthritis research, it is especially suited to assess joint hypersensitivity in rodent knees or ankles, providing a sensitive and reproducible endpoint for analgesic and anti-inflammatory drug evaluation.
Research Applications
The PAM device is specifically designed and validated for measuring joint pain threshold in arthritis models. It is used to assess mechanical hyperalgesia in rodent knees and ankles in models of rheumatoid arthritis, osteoarthritis, and crystal arthropathy, providing a sensitive and reproducible endpoint for analgesic and anti-inflammatory drug evaluation.
.webp)
| Category | Specification |
|---|---|
| Commands | Via soft buttons and pedal |
| Force Ranges | 0–500 gf, 0–1,500 gf |
| Force Resolution | 0.1 gf steps |
| Latency Time | 0.1 s steps |
| Auto Stop | End of pressure or time limit (5–25 s adjustable) |
| PC Connection | USB with DCA3 Software (included) |
| Power | Battery, USB, or mains (100–240 VAC, 50–60 Hz) |
| Operating Temperature | 10°C to 40°C, 5–95% RH |
| Weight | 0.8 kg |
| Dimensions | 12(w) × 15(d) × 4.5(h) cm |
| Warranty | 12 months + 12 months post-registration |
Analgesia
Explore All ProductsPAM Publications
The PAM (Pressure Application Measurement, Cat. 38500) is cited in osteoarthritis, rheumatoid arthritis, fibromyalgia, and musculoskeletal pain research for measuring joint mechanical pain thresholds in rodents. Its design enables precise force application to joints without requiring animal immobilization.
What joints can be assessed with the PAM?
The PAM is designed for rodent joints, particularly the knee and ankle, and has been validated for models of rheumatoid arthritis and osteoarthritis.
What force ranges are available?
Two force ranges are available: 0–500 gf and 0–1,500 gf, with 0.1 gf resolution in both.
What software is included?
DCA3 Software (PC-based) is included for data logging, analysis, and export via USB connection.
How is the measurement stopped?
Measurement stops automatically at the end of the pressure application, after an adjustable time limit (5–25 s), or manually via the foot pedal.
What is the warranty?
12 months standard warranty, extendable to 24 months upon product registration.
Still have questions?
Request for Quote
Please fill in as much details as possible and we will take care of your request as soon as possible
Request for Quote
Please fill in as much details as possible and we will take care of your request as soon as possible