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Hot/Cold Plate
The Hot/Cold Plate has been the gold standard for thermal pain assessment in rodents for decades. Featuring a temperature range from −5° to 65°C and support for constant temperature and ramp protocols via X-Pad software, it covers all analgesic drug screening needs.
The hot/cold plate test has been the gold standard for thermal pain assessment in mouse and rat models for decades. The Ugo Basile system incorporates all the latest technologies to run constant temperature, linear temperature ramps, and complex temperature protocols via included X-Pad software. Plate temperature range spans −5° to 65°C with animal holders of varying heights.
Research Applications
The Hot/Cold Plate is used as a standard assay for thermal nociception and analgesic drug screening in mice and rats. Its ability to run both fixed-temperature and temperature-ramp protocols makes it suitable for studying heat hyperalgesia, cold allodynia, and the pharmacodynamics of analgesic compounds from opioids to COX inhibitors across a wide range of pain models.
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| Category | Specification |
|---|---|
| Commands/Read-out | 4.3" touch-screen (Resistive), PC |
| Temperature Range | –5.0°C to +65°C (0.1°C steps) |
| Accuracy | ±0.2°C |
| Operating Modes | Fixed temperature, Ramp, Silent, Fast Ramp, Custom Ramp |
| Experiment Duration | Max 999.9 seconds |
| Data Acquisition | Via X-PAD software (included) |
| Data Output | Results table in .csv |
| TTL Output | Temperature, Start, Stop |
| Warranty | 12 months + 12 months post-registration |
Analgesia
Explore All ProductsHot/Cold Plate Publications
The Ugo Basile Hot/Cold Plate (Cat. 35150) is cited in thousands of thermal pain studies screening analgesic and anti-nociceptive compounds. Its wide temperature range (−5°C to +65°C), ramping modes, and multi-endpoint scoring (paw lick, jump, vocalization) make it a versatile platform for hot, warm, and cold allodynia research.
What temperature protocols are supported?
The Hot/Cold Plate supports fixed temperature, linear ramp (heating or cooling), Silent mode, Fast Ramp, and Custom Ramp protocols via X-PAD software.
What is the temperature range and accuracy?
Temperature range is −5.0°C to +65°C in 0.1°C steps with ±0.2°C accuracy.
What animals can be tested?
The Hot/Cold Plate is suitable for both mice and rats, with animal holders of varying heights available for different species.
What data outputs are available?
Results are exported in .csv format via USB flash drive. TTL outputs for Temperature, Start, and Stop allow integration with external recording systems.
What is the warranty?
12 months standard warranty, extendable to 24 months upon product registration.
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