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Analgesy-Meter
The Analgesy-Meter measures paw pressure according to the Randall-Selitto test, enabling rapid screening of analgesic drugs in healthy and inflamed rodent models. A classical instrument in preclinical pharmacology with force ranges up to 750 grams.
The Analgesy-Meter measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, enabling rapid and precise screening of analgesic drugs for anti-nociceptive studies in healthy or inflamed limbs. A classical instrument widely used in preclinical pharmacology for over 50 years.
Research Applications
The Analgesy-Meter measures mechanical pain threshold in the paw according to the Randall-Selitto method, and is used for screening analgesic drugs in both healthy and inflamed rodent models. It is particularly suited for evaluating anti-nociceptive activity in carrageenan-induced and Complete Freund’s Adjuvant (CFA) inflammatory pain models.
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| Category | Specification |
|---|---|
| Power Requirements | 115 V or 230 V, 50/60 Hz, 15 W |
| Operating Temperature | 10°C to 40°C |
| Sound Level | Negligible |
| Start/Stop | By Pedal Switch |
| Force Range (37215) | 0 to 750 g (in 3 ranges: 250/500/750) |
| Force Range (37216) | 0 to 375 g (in 3 ranges: 125/250/375) |
| Weight | 3.3 kg |
| Dimensions | 46 × 16 × 14 cm |
| Warranty | 12 months + 12 months post-registration |
Analgesia
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The Analgesy-Meter (Cat. 37215) implements the Randall-Selitto paw-pressure test and is cited across thousands of analgesic drug screening studies. It applies steadily increasing mechanical pressure to rat or mouse paws to determine nociceptive thresholds in normal, inflamed, and neuropathic conditions.
What is the Randall-Selitto paw-pressure test?
The Randall-Selitto test measures the force required to elicit a paw withdrawal response when increasing pressure is applied to the dorsal surface of the rodent paw, providing a direct measure of mechanical nociceptive threshold.
What are the two versions of the Analgesy-Meter?
Model 37215 measures force up to 750 g (in 3 ranges: 250/500/750 g), while model 37216 measures up to 375 g (in 3 ranges: 125/250/375 g) for more sensitive measurements.
How is the instrument operated?
Start and stop are controlled via a foot pedal switch, keeping both hands free to handle the animal and position the instrument.
Is the Analgesy-Meter suitable for inflamed paws?
Yes, the Analgesy-Meter is validated for use on both healthy and inflamed limbs, including carrageenan-induced and CFA inflammatory pain models.
What is the warranty?
12 months standard warranty, extendable to 24 months upon product registration.
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