ECT Unit – Electroconvulsive Threshold Detection

A constant-current stimulator for electroconvulsive seizures in mice and rats. 0 to 99 mA with impedance checked before every shock, ear-clip electrodes as standard and corneal electrodes for the 6 Hz model.

ECT Unit – Electroconvulsive Threshold Detection

What is the ECT Unit?

A constant-current stimulator for inducing electroconvulsive seizures in mice and rats. Current is set from 0 to 99 mA, and feedback circuitry holds it constant against changes in electrode contact. Animal impedance is measured and displayed before the shock, with a warning when it is too high to deliver the set current.

Ear-clip electrodes come standard, for running several animals quickly. Corneal electrodes are an option, and with them the unit runs the 6 Hz corneal model used in drug-resistant seizure work.

Key Features

  • Current 0 to 99 mA in 1 mA steps, ±2%
  • Pulse width 0.1 to 0.9 ms, frequency 1 to 299 pulses/s
  • Shock duration 0.1 to 9.9 s
  • Impedance read-out 0 to 199 kΩ before stimulation
  • Analog output to an oscilloscope or acquisition system
  • Optional Biphasic Unit that inverts every other pulse, with maximum frequency then 100 Hz
  • Any electrode type can be connected; custom electrodes on request

Why constant current

With a constant-voltage stimulator, the delivered current changes with electrode contact from animal to animal, and the measured threshold moves with it. Holding the current fixed is what makes a seizure threshold comparable across a group.

Where it is used

Seizure threshold testing, anticonvulsant screening and the 6 Hz psychomotor seizure model. Also general screening of neurotropic compounds and studies of CNS depressant or stimulant drug effects.

Which seizure model is the study built on?

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Technical Specifications

Catalog Number57800
SpeciesMouse, rat
Current0 to 99 mA in 1 mA steps, ±2%, constant pulses
Pulse Width0.1 to 0.9 ms in 0.1 ms steps, ±1%
Pulse Rise and Fall Time20 µs
Pulse Voltage3 kV max
Frequency1 to 299 pulses/s in 1 pulse/s steps, ±1%
Shock Duration0.1 to 9.9 s in 0.1 s steps, ±1%
Output Resistance0 to 30 kΩ at max current
Impedance Display0 to 199 kΩ, 1 kΩ resolution
Power115/230 V, 50/60 Hz, 100 W
Warranty12 months, plus 12 months on product registration

Part Numbers

57800ECT Unit, complete with standard accessories
57800-001Pulse generator
57800-002Set of auricular electrodes
57800-320Set of felt pads for auricular electrodes
E-AU 041USB pen drive with instruction manual
57800-003Set of corneal electrodes (option)

Applications

  • Electroconvulsive seizure threshold determination
  • 6 Hz corneal psychomotor seizure model
  • Anticonvulsant and neurotropic compound screening
  • CNS depressant and stimulant drug effects
  • Endocrine studies of the nervous system and hypophysis

ECT Unit 57800 - front view with electrodes
ECT Unit 57800 - angled view
ECT Unit 57800 - side view with ear-clip electrodes
ECT Unit 57800 - control panel

Research on Epilepsy and Seizures

צפו בכל המוצרים
Peer-reviewed research using the Ugo Basile ECT Unit

Published seizure studies using the Ugo Basile 57800 ECT Unit, including electroconvulsive threshold testing and the 6 Hz psychomotor seizure model in mice and rats.

Ear-clip or corneal electrodes?

Ear-clip (auricular) electrodes come standard and are quick for running several animals. Corneal electrodes are an option. The 6 Hz psychomotor seizure model is run with corneal stimulation.

Why does impedance matter?

The unit drives a set current, but only up to its voltage limit. With poor electrode contact, the set current cannot be delivered. The ECT Unit measures impedance before the shock and warns when it is too high.

Can the stimulus be recorded?

Yes. An analog output connects to an oscilloscope or a data acquisition system.

What does the Biphasic Unit do?

It sits between the ECT Unit and the animal and inverts every other pulse. With it, the maximum frequency drops to 100 Hz.

Is it available in Israel with local support?

Yes. NBT distributes Ugo Basile in Israel. Installation, training and service are local.

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